The aim of this study was to detect the haematological abnormalities in apparently healthy male donors to establish a safety for both donors and recipient and also to transfuse safe blood and blood products and to know the normal range of white blood cells, hemoglobin with red cell indices and platelets count. Venous blood samples were taken from 500 apparently healthy males donors and the haematological parameters were measured using an automated cell counter (sysmex KN21), haemoglobin concentration, red blood cells count, haemotocrit, mean corpuscular volume, mean corpuscular haemoglobin, mean corpuscular haemoglobin concentration, white blood counts, platelet counts, accompanied by peripheral blood films were assessed to detect any haematological abnormalities. For haemoglobin estimation copper sulphate method is routinely performed in Wad medanni blood bank. Although this method is not properly performed. In this study it was found that a considerable numbers of donors were anaemic, leucopenic, thrombocytopenic, few numbers with leucocytosis and thrombocytosis, high eosinophil percentage and lymphocyte percentage with reactive forms also detected.