This comprehensive reference presents cutting-edge and long-ranging research in computational systems biology. It is written by leading experts and covers a range of topics from modeling and learning biological systems to the impact of computational systems biology on drug design and medicine. Chapters provide a multidisciplinary approach and range from analysis, modeling, prediction, reasoning, inference, and exploration of biological systems to the applications of computational systems biology. These chapters target topics and solutions in computer science, mathematics, physics, biology, and the pharmaceutical and biomedical areas.

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